Navigation PerferencesNuvi 2465 comes with some of the features you found in nuvi 3790. In addition to that, there are extras goodies which only can be found in this 2xxx series.
Under "Setting" -> "Navigation" -> "Car", you'll see these options

Under the "nüRoute", some interesting new features like ERP cost saving (for SG users), custom avoidance (by area) and myTrends
From Garmin Website wrote:
With myTrends, when you save your regular destinations in your “Favorites,” your nüvi 2465 will, over time, begin to figure out where you’re going even without your telling it! It provides time of arrival and relevant traffic information. So whether you’re driving to and from work or a regularly scheduled weekly event, your nüvi 2465 will help you get there on time. No subscription or additional cost required.
Note: myTrends ONLY works for locations that are saved as Favorites
Avoidance by areaYou can now add avoidance by area to suit your own routing.

Follow the setup guide to set the 1st corner and the diagonal corner, you can have the area out of your routing consideration.
The red wire mash like avoidance area will show up as well during navigation mode



Map ThemeIf you prefer you own color theme for map, you can try out some of the preset map color themes.

Bluetooth hands free setYou can use your Nuvi 2465 as hands free set during navigation. After pairing up, an extra phone icon show up in the main menu. The phone functions are shown as attached picture. The link to your phone contact list is pretty fast. No problem showing chinese character sets from your phone contact list as well.

Built-in CompassNuvi 2465 come with built-in compass, which means you can find your direction without gps satelite signal. Useful for the pedestrian mode.
ScreenshotAll captured images are now save in
png format.
Screenshot option can be saved and you don't have to enable it every time you turn on the nuvi.